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November is finally here, and in college football, that means some big games with two top-10 matchups highlighting the slate. It also brings the return of the Pac-12 and the MAC, giving fans the busiest schedule of the season. This week features games on Wednesday, Thursday, Friday, and Saturday.
New Heisman Frontrunner
With Clemson quarterback Trevor Lawrence missing last week’s game and this week’s game with COVID, he is no longer the betting favorite to win the Heisman trophy. Lawrence was -150 before getting sick and now has the third-best odds at +300. He was passed by Alabama quarterback Mac Jones (+125) and Ohio State quarterback Justin Fields (+150) this weekend.
Showdown in South Bend
The biggest game this weekend features No. 1 Clemson (7-0) at No. 4 Notre Dame (6-0). Even without Lawrence, the Tigers are favored by six points on the road against the Irish. The game kicks off at 7:30 p.m. ET on NBC, and the winner is virtually locked into the ACC Championship game.
High Stakes in the Cocktail Party
The SEC East once again goes through the World’s Largest Outdoor Cocktail Party in Jacksonville, FL, as No. 5 Georgia (4-1) plays No. 8 Florida (3-1). The Bulldogs are favored by 3.5 points in the 3:30 p.m. ET kickoff on CBS. Whoever wins this game controls their destiny for the SEC East title and a trip to Atlanta to likely face No. 2 Alabama in December’s SEC title game.
Big Ten Battle
The only game with two ranked teams in the Big Ten this weekend is No. 13 Indiana (2-0) hosting No. 23 Michigan (1-1) at Noon ET on FS1. The upstart Hoosiers are +3 at home against the Wolverines, who were stunned at home by Michigan State on Saturday.
Welcome Back Pac 12
No. 20 USC (-10.5) gets the Pac-12 season underway with a Noon ET game on FOX against Arizona State. No. 12 Oregon is favored by 13 points at home against Stanford with a 7:30 p.m. ET kickoff on ABC. Oregon and USC are co-favorites to win the Pac-12 at +200 with Washington at +400 and Utah at +700.
There are two late games in the Pac-12 as well. Oregon State is favored by 1.5 points at home against Washington State with a 10:30 p.m. kickoff on FS1. Meanwhile, California is favored by one point at home against Washington with a 10:30 p.m. ET kickoff on ESPN.
Top 25 Tilt in Boise
The big Friday night game comes in the Group of Five as No. 9 BYU (7-0) travels to No. 21 Boise State (2-0). BYU can make a statement for the playoffs with a win, and they are favored by 2.5 points for the 9:45 p.m. ET game that will be televised on FS1.
Buffalo is favored to win the MAC at +200, and they play at Northern Illinois (+10) Wednesday at 7:00 p.m. ET on ESPN2. Ohio has the next best odds at +350, and they open the season Wednesday at Central Michigan (-1) at 7:00 p.m. ET on ESPN.